Question:
Regarding PCOD (polycystic ovarian disease), all of the following are true except?
Regarding PCOD (polycystic ovarian disease), all of the following are true except?
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A grossly raised level here would point you toward a prolactinoma instead.
Updated On: Jun 24, 2026
- High LH/FSH ratio
- High DHEAS
- Markedly high prolactin
- Raised LH
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The Correct Option is C
Solution and Explanation
Step 1: Recall the hormonal profile of PCOD. There is increased pulsatile GnRH leading to a raised LH and a reversed LH/FSH ratio (classically about 2:1 or more).
Step 2: Androgens are increased; adrenal androgen DHEAS is mildly to moderately elevated in a proportion of patients, and ovarian androgens (testosterone) are raised, producing hyperandrogenism.
Step 3: Consider prolactin. A mild elevation in prolactin can occasionally be seen, but a MARKEDLY high prolactin is not a feature of PCOD. A markedly raised prolactin points to a prolactinoma or other cause of hyperprolactinaemia, which is a separate differential. Therefore markedly high prolactin is the false statement.
Step 4: Hence the exception is markedly high prolactin.
Answer: Option C, Markedly high prolactin.
Step 2: Androgens are increased; adrenal androgen DHEAS is mildly to moderately elevated in a proportion of patients, and ovarian androgens (testosterone) are raised, producing hyperandrogenism.
Step 3: Consider prolactin. A mild elevation in prolactin can occasionally be seen, but a MARKEDLY high prolactin is not a feature of PCOD. A markedly raised prolactin points to a prolactinoma or other cause of hyperprolactinaemia, which is a separate differential. Therefore markedly high prolactin is the false statement.
Step 4: Hence the exception is markedly high prolactin.
Answer: Option C, Markedly high prolactin.
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