Step 1: Concept
Controlled substances are categorized into schedules based on their potential for abuse and medicinal value.
Step 2: Meaning
Schedule II drugs have a high potential for abuse and severe psychological or physical dependence but have currently accepted medical uses.
Step 3: Analysis
Due to the high risk of addiction and misuse associated with these drugs, strict regulations prohibit the refilling of Schedule II prescriptions. A new prescription must be issued for every dispense.
Step 4: Conclusion
Therefore, refilling is strictly prohibited for Schedule II controlled substances.
Final Answer: (C)