Question:
Medical treatment for variceal bleeding is by which of the following?
Medical treatment for variceal bleeding is by which of the following?
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Think of a splanchnic vasoconstrictor that lowers portal pressure.
Updated On: Jun 24, 2026
- Octreotide
- Pantoprazole
- Desmopressin
- Somatotropin
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The Correct Option is A
Solution and Explanation
Step 1: Understand the pathophysiology. Variceal bleeding (esophageal/gastric varices) is driven by portal hypertension, so medical control depends on lowering portal and splanchnic blood flow.
Step 2: Identify the right drug class. Splanchnic vasoconstrictors reduce portal inflow and pressure. Octreotide, a somatostatin analogue, causes splanchnic vasoconstriction and is the standard pharmacological agent used to control acute variceal hemorrhage.
Step 3: Eliminate the other options. Pantoprazole is a proton pump inhibitor used for peptic ulcer and acid-related bleeding, not portal hypertension. Desmopressin is used in von Willebrand disease and mild hemophilia, not varices. Somatotropin (growth hormone) has no role in variceal bleed.
Step 4: Conclusion. Octreotide is the correct medical treatment for variceal bleeding.
Step 2: Identify the right drug class. Splanchnic vasoconstrictors reduce portal inflow and pressure. Octreotide, a somatostatin analogue, causes splanchnic vasoconstriction and is the standard pharmacological agent used to control acute variceal hemorrhage.
Step 3: Eliminate the other options. Pantoprazole is a proton pump inhibitor used for peptic ulcer and acid-related bleeding, not portal hypertension. Desmopressin is used in von Willebrand disease and mild hemophilia, not varices. Somatotropin (growth hormone) has no role in variceal bleed.
Step 4: Conclusion. Octreotide is the correct medical treatment for variceal bleeding.
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