Question

Match List I with List II 

 

• A. A-IV, B-III, C-II, D-I
• B. A-IV, B-II, C-I, D-III
• C. A-I, B-II, C-III, D-IV
• D. A-II, B-IV, C-I, D-III

Hint:

Imidocarb dipropionate is the classic drug of choice for treating tick-borne Babesiosis (B-II).
Pairing this single association narrows down the correct answer to option (B) quickly.

Answer 1

The Correct Option is B

Step 1: Understanding the Concept:
Antiprotozoal drugs are categorized based on their chemical structures and their specific efficacy against targeted protozoan groups (coccidia, piroplasms, flagellates, and amoebae).

Step 2: Detailed Explanation:
Let us match each disease with its standard therapeutic agent:
- A. Coccidiosis: This enteric infection caused by Eimeria or Isospora spp. in animals is treated and prevented using coccidiocides like Toltrazuril, which disrupts the intracellular stages of the parasite.
Thus, A matches with IV.
- B. Babesiosis: This tick-borne disease caused by intra-erythrocytic Babesia parasites is treated using the carbanilide derivative Imidocarb (typically as imidocarb dipropionate).
Thus, B matches with II.
- C. Leishmaniasis: Canine and human visceral leishmaniasis is treated primarily with Pentavalent antimony compounds (such as sodium stibogluconate or meglumine antimoniate).
Thus, C matches with I.
- D. Amoebiosis: Infections caused by Entamoeba histolytica are clinically treated using the nitroimidazole derivative Metronidazole, which causes DNA strand breakage in anaerobic environments.
Thus, D matches with III.

Step 3: Final Answer:
Matching these parameters yields the sequence A-IV, B-II, C-I, D-III, which corresponds to option (B).