Question:

Mass chemoprophylaxis in an endemic area is recommended for all of the following, except:

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Leprosy control uses case detection and MDT, not whole population drugging.
Updated On: Jun 24, 2026
  • Yaws
  • Leprosy
  • Trachoma
  • Filaria
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The Correct Option is B

Solution and Explanation

Step 1: Define mass chemoprophylaxis.
Mass chemoprophylaxis means giving a drug to a whole population in an endemic area to prevent or interrupt transmission, regardless of individual disease status.

Step 2: Check each disease.
Yaws: mass treatment with penicillin (azithromycin in newer programmes) of entire endemic communities is a classic mass prophylaxis approach. Recommended.
Trachoma: the SAFE strategy includes mass administration of azithromycin (the A component) to whole endemic communities. Recommended.
Filaria: mass drug administration with DEC and albendazole to the entire eligible population in endemic districts is the cornerstone of elimination. Recommended.

Step 3: Identify the exception.
Leprosy control relies on early case detection and multidrug therapy of cases and contacts, not on giving drugs to the entire population. Classical mass chemoprophylaxis is not the recommended population wide strategy for leprosy. So leprosy is the exception.

Answer: Option B.
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