Question:

Lendrum stain (Phloxine-Tartrazine) is done at autopsy for the diagnosis of?

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Phloxine-Tartrazine highlights fetal squames in maternal lung vessels.
Updated On: Jun 24, 2026
  • Air embolism
  • Fat embolism
  • Amniotic fluid embolism
  • None
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The Correct Option is C

Solution and Explanation

Step 1: Diagnosis of amniotic fluid embolism at autopsy depends on demonstrating fetal elements within the maternal pulmonary vasculature using special stains on sections of lung and other organs.

Step 2: The Lendrum stain (Phloxine-Tartrazine) is used to detect fetal squames (squamous cells), which appear in the maternal lung capillaries in amniotic fluid embolism.

Step 3: Complementary stains include Alcian Blue to detect mucin and Sudan Black or Oil Red O to detect lipid (vernix caseosa), together confirming the presence of amniotic fluid debris.

Step 4: Air embolism and fat embolism are diagnosed by other techniques (for example, special dissection and water-trap tests for air, and Oil Red O for systemic fat), so amniotic fluid embolism is the correct answer.
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