Step 1: The palm has two potential fascial spaces deep to the long flexor tendons, separated by a fibrous septum running to the third metacarpal: the thenar space (radial) and the mid palmar space (ulnar).
Step 2: The thenar space communicates with the index finger through the lumbrical canal, while the mid palmar space communicates with the middle, ring and little fingers.
Step 3: Therefore a deep infection of the index finger tracks into and collects in the thenar space, whereas infection of the middle, ring or little finger spreads to the mid palmar space.
Step 4: The hypothenar space is small and not a usual site of spread, so the correct answer is the thenar space.