Step 1: Understanding the Concept:
Systemic homeostasis: Claude Bernard's milieu intƩrieur and Walter Cannon's homeostasis integrate passive biophysical transport gradients with central neuroendocrine feedback control loops.
Step 2: Detailed Explanation:
Mechanisms maintaining physiological Homeostasis:
1. Cellular Biophysical Transport (A, B, C): Simple and facilitated diffusion, maintenance of concentration gradients across cell membranes (via $\text{Na}^+/\text{K}^+$-ATPase), and pressure gradients (hydrostatic and oncotic Starling forces) maintain fluid, electrolyte, and nutrient exchange.
2. Integrative Systemic Control (D, E): The Nervous System (rapid reflex autonomic regulation of blood pressure, respiration, body temperature) and the Endocrine System (sustained hormonal regulation of blood glucose, calcium, osmolarity, and metabolic rate) coordinate negative feedback control.
Therefore, all processes A, B, C, D, and E maintain homeostasis.
Step 3: Final Answer:
Hence, homeostasis is maintained by All A, B, C, D and E, matching option (D).