Haemophilia is an example of
- Y-linked disorder
- XY-linked inheritance
- Autosomal inheritance
- Sex-linked recessive inheritance
The Correct Option is D
Solution and Explanation
Top Questions on Principles of Inheritance and Variation
Which of the following statements are correct about Klinefelter’s Syndrome?
A. This disorder was first described by Langdon Down (1866).
B. Such an individual has overall masculine development. However, the feminine development is also expressed.
C. The affected individual is short statured.
D. Physical, psychomotor and metal development is retarded. E. Such individuals are sterile.Choose the correct answer from the options given below:
- NEET (UG) - 2023
- Biology
- Principles of Inheritance and Variation
- Which one of the following symbols represents mating between relatives in human pedigree analysis?
- NEET (UG) - 2023
- Biology
- Principles of Inheritance and Variation
- The phenomenon of pleiotropism refers to
- NEET (UG) - 2023
- Biology
- Principles of Inheritance and Variation
- In Turner's Syndrome, during cell division, which type of Aneuploidy is seen?
- GUJCET - 2023
- Biology
- Principles of Inheritance and Variation
Why was Drosophila melanogaster used for studies in Genetics ?
(A) They could be cultured easily in the monastery(B) They showed many contrasting traits(C) The generation time was one year(D) There was clear differentiation of sexes(E) Very few progeny were produced in a single matingChoose the correct answer from the options given below :
- CUET (UG) - 2022
- Biology
- Principles of Inheritance and Variation
Questions Asked in OJEE exam
- Transfer of genetic material from one bacterium to another through contact is
- OJEE - 2013
- biological classification
- The term episome refers to a type of
- OJEE - 2013
- biological classification
- Teichoic acid is present in which cell component of bacteria
- OJEE - 2013
- Prokaryotic Cells
- Which group includes protozoa, protistan algae and slime moulds
- OJEE - 2013
- biological classification
- Enzymes present in gastric juice of stomach are
- OJEE - 2013
- Digestion and absorption
Concepts Used:
Principles of Inheritance and Variation - Mutation
A Mutation is a change in the sequence of our DNA base pairs caused by numerous environmental stimuli such as UV light or mistakes during DNA replication. Germline mutations take place in the eggs and sperm and can be passed onto offspring, whereas somatic mutations take place in body cells and are not passed on.
Types of Mutations
There are three types of mutations, which are as follows:
Silent mutation
It refers to any change in DNA sequence that has no effect on the amino acid sequence in a protein or the functions that a protein performs. There is no phenotypic indication that a mutation has occurred.
Nonsense mutation
When there is a change in the sequence of base pairs due to a point mutation, that results in a stop codon. This leads to a protein that is either shortened or non-functional.
Missense mutation
A missense mutation occurs when a point mutation causes a change in the codon, which then codes for another amino acid.
The mutation is caused by the following factors:
Internal Causes
When DNA copies incorrectly, the majority of mutations occur. Evolution occurs as a result of all of these mutations. DNA makes a copy of itself during cell division. When a copy of DNA isn't flawless, it's called a mutation since it differs somewhat from the original DNA.
External Causes
When certain chemicals or radiations are used to break down DNA, it causes the DNA to break down. The thymine dimers are broken by UV radiation, resulting in altered DNA.
SUBSCRIBE TO OUR NEWS LETTER
