Question:
H1 receptor protein in humans is made up of:
H1 receptor protein in humans is made up of:
Updated On: Jul 14, 2026
- 487 Aminoacids
- 390 Aminoacids
- 445 Aminoacids
- 359 Aminoacids
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The Correct Option is A
Approach Solution - 1
The correct option is (A): 487 Aminoacids.
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Approach Solution -2
The human histamine H1 receptor is a G-protein coupled receptor, and its gene encodes a protein of a specific, fixed length. Let's weigh the four amino acid counts given.
- 487 Aminoacids: This is the length reported for the human H1 receptor protein, a seven-transmembrane G-protein coupled receptor with a relatively long third intracellular loop compared to some other histamine receptor subtypes.
- 390 Aminoacids: This count is shorter than the actual H1 receptor and does not correspond to its documented sequence length.
- 445 Aminoacids: This value is closer to the length reported for the human H2 receptor, a smaller GPCR than H1, rather than H1 itself.
- 359 Aminoacids: This is close to the length reported for the human H4 receptor, one of the smaller histamine receptor subtypes, not H1.
Comparing the sizes of the four histamine receptor subtypes, H1 is documented as the longest at 487 amino acids.
The correct answer is 487 Aminoacids.
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