Question:
Gradual decrease in response, on repeated administration of drug is called
Gradual decrease in response, on repeated administration of drug is called
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Tolerance = Gradual loss of drug responsiveness over time; Tachyphylaxis = Rapidly developing acute tolerance.
Updated On: Sep 15, 2026
- Tolerance
- Tachyphylaxis
- Desensitization
- Withdrawal syndrome
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The Correct Option is A
Solution and Explanation
Step 1: Understanding the Concept:
Pharmacodynamics describes changes in biological receptor responsiveness following chronic or repeated xenobiotic administration.
Step 2: Detailed Explanation:
Drug tolerance is the gradual reduction in pharmacological responsiveness following repeated or prolonged administration of a drug, requiring increasing doses to produce the original magnitude of effect.
Tachyphylaxis is rapid, acute desensitization occurring after only a few doses.
Step 3: Final Answer:
Therefore, a gradual decrease in drug response is called tolerance.
Pharmacodynamics describes changes in biological receptor responsiveness following chronic or repeated xenobiotic administration.
Step 2: Detailed Explanation:
Drug tolerance is the gradual reduction in pharmacological responsiveness following repeated or prolonged administration of a drug, requiring increasing doses to produce the original magnitude of effect.
Tachyphylaxis is rapid, acute desensitization occurring after only a few doses.
Step 3: Final Answer:
Therefore, a gradual decrease in drug response is called tolerance.
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