Question:
Given below are two statements
Statement I: The envelope spikes of all paramyxoviruses are composed of the fusion protein (F) and HN glycoproteins
Statement II: F is responsible for the fusion of the viral envelope with the plasma membrane of the host cell
In light of the above statements, choose the correct answer from the options given below:
Given below are two statements
Statement I: The envelope spikes of all paramyxoviruses are composed of the fusion protein (F) and HN glycoproteins
Statement II: F is responsible for the fusion of the viral envelope with the plasma membrane of the host cell
In light of the above statements, choose the correct answer from the options given below:
Statement I: The envelope spikes of all paramyxoviruses are composed of the fusion protein (F) and HN glycoproteins
Statement II: F is responsible for the fusion of the viral envelope with the plasma membrane of the host cell
In light of the above statements, choose the correct answer from the options given below:
Show Hint
While the Fusion (F) protein is conserved across all paramyxoviruses, the attachment protein varies: HN (Hemagglutinin-Neuraminidase), H (Hemagglutinin only), or G (Glycoprotein).
Updated On: Aug 13, 2026
- Both Statement I and Statement II are true
- Both Statement I and Statement II are false
- Statement I is true and Statement II is false
- Statement I is false and Statement II is true
Show Solution
Verified By Collegedunia
The Correct Option is D
Solution and Explanation
Step 1: Understanding the Concept:
The family Paramyxoviridae consists of enveloped, single-stranded, negative-sense RNA viruses.
Their envelope contains surface glycoprotein spikes that mediate attachment to the host cell and fusion with the host cell membrane.
Detailed Explanation:
Let us analyze both statements:
- Statement I: The statement asserts that the envelope spikes of all paramyxoviruses are composed of Fusion (F) protein and Hemagglutinin-Neuraminidase (HN) glycoproteins. While all paramyxoviruses possess the F protein, the attachment protein varies by genus. Some genera utilize the HN glycoprotein (such as Respirovirus and Avulavirus), but others have different glycoproteins. For example, Morbilliviruses (like Canine Distemper Virus) use a Hemagglutinin (H) protein lacking neuraminidase activity, and Henipaviruses (like Nipah virus) use an attachment Glycoprotein (G) that lacks both hemagglutinating and neuraminidase activities. Therefore, Statement I is false.
- Statement II: The Fusion (F) glycoprotein is a class I viral fusion protein. It undergoes conformational changes that insert a hydrophobic fusion peptide into the host cell membrane, mediating pH-independent fusion of the viral envelope with the plasma membrane of the host cell. Therefore, Statement II is true.
Step 2: Final Answer:
Statement I is false, and Statement II is true, which corresponds to Option (D).
The family Paramyxoviridae consists of enveloped, single-stranded, negative-sense RNA viruses.
Their envelope contains surface glycoprotein spikes that mediate attachment to the host cell and fusion with the host cell membrane.
Detailed Explanation:
Let us analyze both statements:
- Statement I: The statement asserts that the envelope spikes of all paramyxoviruses are composed of Fusion (F) protein and Hemagglutinin-Neuraminidase (HN) glycoproteins. While all paramyxoviruses possess the F protein, the attachment protein varies by genus. Some genera utilize the HN glycoprotein (such as Respirovirus and Avulavirus), but others have different glycoproteins. For example, Morbilliviruses (like Canine Distemper Virus) use a Hemagglutinin (H) protein lacking neuraminidase activity, and Henipaviruses (like Nipah virus) use an attachment Glycoprotein (G) that lacks both hemagglutinating and neuraminidase activities. Therefore, Statement I is false.
- Statement II: The Fusion (F) glycoprotein is a class I viral fusion protein. It undergoes conformational changes that insert a hydrophobic fusion peptide into the host cell membrane, mediating pH-independent fusion of the viral envelope with the plasma membrane of the host cell. Therefore, Statement II is true.
Step 2: Final Answer:
Statement I is false, and Statement II is true, which corresponds to Option (D).
Was this answer helpful?
0
0
Top ICAR AIEEA Veterinary Science Questions
- In ox vallate papillae are
- Spiral colon is characteristic of
- Assertion (A) : Stratum lucidum is translucent layer present between stratum spinosum and stratum granulosum
Reasoning (R) : Stratum lucidum is translucent due to presence of eledin protein.
In light of the above statements, choose the correct answer from the options given below. - Statement (I): Keratinocytes contain melanin pigment in the form of melanosomes.
Statement (II): Melanin pigment is produced by keratinocytes with the help of Tyrosinase enzyme.
In light of the above statements, choose the most appropriate answer from the options given below. - Which of the following is true for mast cells?
(A). These cells are common in loose connective tissue.
(B). These cells take metachromatic stain.
(C). These cells are rich in histamine, heparin and proteases.
(D). These cells contain basophilic cytoplasmic granules.
Choose the correct answer from the options given below:
View More Questions
Top ICAR AIEEA Virology and Mycology Questions
- Feline panleukopenia is also known as
- Most common form of Aspergillosis in horses is
- Which of the following poxvirus infections is NOT an animal pox?
- Which of the following statements is INCORRECT with respect to Bovine Herpesvirus-1 (BoHV-1) infection?
- Which of the following structural component is found in all animal viruses?
View More Questions
Top ICAR AIEEA Questions
- Which of the following statements is false?
- Which of the following is an example of an inventory?
- According to Adam Smith, productivity gains could be brought about through .
- The supply curve for an artificially scarce good is .
- Which of the following would not be considered an opportunity cost of paid employment?
View More Questions