Question

Given below are two statements:
Statement I: Kumri is a condition caused by Setaria digitata in cattle
Statement II: The pathogenic effects in cattle are mainly due to erratic migration of mature worms in the Central Nervous System
In the light of the above statements, choose the most appropriate answer from the options given below

• A. Both Statement I and Statement II are true
• B. Both Statement I and Statement II are false
• C. Statement I is correct but Statement II is false
• D. Statement I is incorrect but Statement II is true

Hint:

Kumri Lumbar Paralysis: Caused by aberrant larval migration of Setaria digitata in HORSES, SHEEP, and GOATS (abnormal hosts). Cattle are asymptomatic natural hosts.

Answer 1

The Correct Option is B

Step 1: Understanding the Concept:
Cerebrospinal nematodiasis (Kumri) occurs when immature filarial worms undergo aberrant erratic migration in abnormal/accidental hosts (horses, sheep, goats), whereas cattle are natural non-symptomatic hosts.

Step 2: Detailed Explanation:
Pathobiology of Kumri (Cerebrospinal Nematodiasis):
1. Statement I: Setaria digitata is a natural, essentially non-pathogenic peritoneal parasite of cattle (its definitive natural host). Kumri is a progressive lumbar paralysis/ataxia occurring in horses, sheep, and goats (abnormal/accidental hosts), NOT in cattle. Hence, Statement I is false.
2. Statement II: In cattle, mature Setaria live harmlessly in the peritoneal cavity without CNS invasion. Severe neuro-pathology (traumatic malacia and focal encephalomyelomalacia) occurs exclusively in accidental hosts due to erratic migration of immature microfilarial larvae, not mature worms in cattle. Hence, Statement II is false.

Step 3: Final Answer:
Thus, Both Statement I and Statement II are false, corresponding to option (B).