Step 1: Understanding the Concept:
Etiopathogenesis and clinical triad of lower urinary tract inflammatory disease (cystitis) in domestic animals.
Step 2: Detailed Explanation:
1. Statement I: In all domestic animals (cattle, dogs, cats, horses), Cystitis is overwhelmingly caused by ascending bacterial infection (predominantly uropathogenic Escherichia coli, Corynebacterium renale, Proteus, Staphylococcus, and Enterococcus). Claiming it is 'NOT associated with bacterial infection' is completely false. Hence, Statement I is incorrect.
2. Statement II: Inflammation of the urinary bladder trigone and mucosa consistently causes the classic Lower Urinary Tract Signs (LUTS) Triad: Pollakiuria (frequent urination), Dysuria Stranguria (painful, difficult straining), and Hematuria (blood in urine). Hence, Statement II is true.
Step 3: Final Answer:
Therefore, Statement I is incorrect but Statement II is true, corresponding to option (D).