Step 1: Understanding the Concept:
Pathogen culturability in vitro depends on whether the organism is a facultative saprophyte or an obligate biotroph.
Step 2: Detailed Explanation:
1. Statement I is INCORRECT: Many cellular plant pathogens are obligate biotrophs that cannot be cultured on synthetic nutrient agar media in vitro (e.g., rust fungi Puccinia, powdery mildews Erysiphe, downy mildews, plasmodiophorids, and fastidious wall-less phytoplasmas).
2. Statement II is TRUE: Non-cellular infectious biological agents (such as plant viruses and sub-viral viroids) are absolute molecular obligate intracellular parasites that possess no independent cellular metabolic machinery and cannot be cultured on cell-free artificial media.
Step 3: Final Answer:
Therefore, Statement I is incorrect but Statement II is true.