Question:

Establishment of the fetoplacental circulation is seen at which day after fertilization?

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Tertiary villi and the first fetal heartbeat appear around day 21 - that starts the fetoplacental circulation.
Updated On: Jun 23, 2026
  • 11 to 13 days
  • 20 to 22 days
  • 7 days
  • 25 to 26 days
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The Correct Option is B

Solution and Explanation

Step 1: The fetoplacental (true placental) circulation begins only after the fetal heart starts beating and the tertiary chorionic villi develop their own vascular network linked to the embryo. Step 2: Following the timeline of events after fertilization: primary villi form around day 13, secondary villi around day 16, and tertiary (vascularised) villi around day 21. Step 3: The fetal heart begins to beat and the fetoplacental circulation is established around day 21 to 22, which corresponds to the 20 to 22 day window in option b. Step 4: The other options are too early: by day 7 only blastocyst attachment is occurring, and around days 10 to 13 the uteroplacental (maternal) circulation and primary villi are being set up, not the fetal circulation. Day 25 to 26 is later than the classic establishment point.
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