Step 1: Endophthalmitis means inflammation of the INTERNAL contents of the eyeball, mainly the intraocular cavities and tissues, usually due to infection.
Step 2: It involves the vitreous and aqueous (the intraocular fluids), the uvea (uveal inflammation), and the adjacent retina. So the uvea, retina, and vitreous are all affected.
Step 3: The sclera is the tough outer coat of the eye. When inflammation extends to involve all coats INCLUDING the sclera and orbital tissues, the condition is called panophthalmitis, not endophthalmitis.
Step 4: Therefore, by definition, endophthalmitis spares the sclera; involvement of the sclera marks a more extensive process (panophthalmitis).
Hence the answer is Option A (Sclera).