Question:
Drugs used in the prophylaxis of migraine include all of the following EXCEPT?
Drugs used in the prophylaxis of migraine include all of the following EXCEPT?
Show Hint
Three are recognised migraine preventives; one is purely an antiepileptic with no preventive role.
Updated On: Jun 24, 2026
- Propranolol
- Flunarizine
- Topiramate
- Levetiracetam
Show Solution
Verified By Collegedunia
The Correct Option is D
Solution and Explanation
Step 1: The question asks which drug is NOT used for migraine prophylaxis. Prophylaxis is preventive therapy given to reduce the frequency and severity of attacks, distinct from acute abortive therapy.
Step 2: Propranolol is a non-selective beta blocker and is a first-line agent for migraine prophylaxis. It reduces attack frequency and is one of the most commonly prescribed preventives.
Step 3: Flunarizine is a calcium channel blocker with proven efficacy in migraine prophylaxis and is widely used, especially in patients with frequent attacks.
Step 4: Topiramate is an antiepileptic drug that is also approved and first-line for migraine prophylaxis; it stabilizes neuronal membranes and reduces cortical excitability.
Step 5: Levetiracetam is an antiepileptic used mainly for seizure control. It is NOT an established agent for migraine prophylaxis. Therefore the correct answer is Levetiracetam.
Conclusion: The printed key marks option D (Levetiracetam), which is medically correct.
Step 2: Propranolol is a non-selective beta blocker and is a first-line agent for migraine prophylaxis. It reduces attack frequency and is one of the most commonly prescribed preventives.
Step 3: Flunarizine is a calcium channel blocker with proven efficacy in migraine prophylaxis and is widely used, especially in patients with frequent attacks.
Step 4: Topiramate is an antiepileptic drug that is also approved and first-line for migraine prophylaxis; it stabilizes neuronal membranes and reduces cortical excitability.
Step 5: Levetiracetam is an antiepileptic used mainly for seizure control. It is NOT an established agent for migraine prophylaxis. Therefore the correct answer is Levetiracetam.
Conclusion: The printed key marks option D (Levetiracetam), which is medically correct.
Was this answer helpful?
0
0
Top NEET PG Pharmacology Questions
- A bronchial asthma patient on inhalational steroids presented with white patchy lesions on the tongue and buccal mucosa. What is the drug that can be used to treat this condition?
- A pregnant woman with a history of bronchial asthma is in the third stage of labor. Which drugs should be avoided in managing postpartum hemorrhage in this mother?
- Name the drug that acts on both the marked areas.
- A patient with a previous history of myocardial infarction and ventricular arrhythmia is ontreatment for a few months. He developed fatigue, dyspnea, and weight gain. He had also developed pulmonary fibrosis. Which of the following drugs is responsible for the side effects mentioned above?
- A young female comes to the emergency department after consuming 100 aspirin tablets.What should be the next step in management?
View More Questions
Top NEET PG Migraine prophylaxis drugs Questions
Top NEET PG Questions
- A patient hailing from Delhi presents with fever, arthralgia, and extensive petechial rash for 3 days. Lab investigations revealed a hemoglobin of 9 g/ dL, a white blood cell count of 9000 cells/mm3, a platelet count of 20000 cells/mm3, and a prolonged bleeding time. The clotting time was normal. What is the most likely diagnosis?
- Which of the following statements is true about Trichomonas vaginalis?
- A lady from West Rajasthan presented with an ulcer surrounded by erythema on the right leg. Microscopy of the biopsy from the edge of the ulcer showed organisms with dark staining nuclei and kinetoplast. What is the most likely causative agent?
- A child presents with a fever and a rash. Urine examination showed cells with owl's eye appearance. What is the most likely diagnosis?
- Infection with Clonorchis sinensis is associated with an increased risk of__?
View More Questions