Question:
Atropine sulphate is contraindicated in the patients suffering from
A. Heart failure
B. Dyspnea
C. Pre-existing tachycardia
D. Vomition
E. Enteritis
Choose the correct answer from the options given below:
Atropine sulphate is contraindicated in the patients suffering from
A. Heart failure
B. Dyspnea
C. Pre-existing tachycardia
D. Vomition
E. Enteritis
Choose the correct answer from the options given below:
A. Heart failure
B. Dyspnea
C. Pre-existing tachycardia
D. Vomition
E. Enteritis
Choose the correct answer from the options given below:
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Atropine Contraindications: Pre-existing Tachycardia (C), Congestive Heart Failure (A), Glaucoma (causes mydriasis and spikes intraocular pressure), and Rumen Atony/Impaction.
Updated On: Sep 7, 2026
- B only
- D and E only
- A and C only
- D only
Show Solution
Verified By Collegedunia
The Correct Option is C
Solution and Explanation
Step 1: Understanding the Concept:
Antimuscarinic anticholinergic contraindications: blocking cardiac vagal inhibitory tone exacerbates tachycardia, increases myocardial oxygen demand, and worsens congestive heart failure.
Step 2: Detailed Explanation:
Pharmacological contraindications of Atropine Sulphate (a competitive muscarinic $M_2/M_3$ receptor antagonist):
1. C. Pre-existing Tachycardia (and Tachyarrhythmias): Atropine blocks $M_2$ receptors on the SA node, releasing the heart from vagal parasympathetic restraint, causing dangerous acceleration of heart rate and shortening diastolic filling time.
2. A. Congestive Heart Failure Myocardial Damage: The induced severe tachycardia drastically increases myocardial oxygen consumption ($\text{MVO}_2$) and precipitates acute decompensation/ischemia in a failing myocardium.
3. (Atropine is indicated to treat vomition and enteritis due to its antispasmodic and antisecretory effects).
Thus, Atropine is contraindicated in conditions A and C only.
Step 3: Final Answer:
Therefore, Atropine is contraindicated in A and C only, corresponding to option (C).
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