Question:
Antiendomysial antibody is used in the screening of?
Antiendomysial antibody is used in the screening of?
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Link this antibody to a gluten driven small bowel disorder.
Updated On: Jun 24, 2026
- Myasthenia gravis
- Autoimmune hepatitis
- Coeliac disease
- Graves disease
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Verified By Collegedunia
The Correct Option is C
Solution and Explanation
Step 1: Coeliac disease is a permanent intolerance of the small intestine to gluten. It is marked by gluten dependent changes in villous morphology and signs of immune activation in the lamina propria of the intestinal mucosa.
Step 2: Serum anti-endomysial antibodies (EMA) are highly suggestive of coeliac disease because they have both high sensitivity and high specificity. They are therefore a key serological screening test for this condition.
Step 3: Other supportive antibodies are tissue transglutaminase and antigliadin antibodies, and the treatment is a strict gluten free diet. Myasthenia gravis is screened with anti-acetylcholine receptor antibodies, autoimmune hepatitis with anti smooth muscle and ANA, and Graves disease with TSH receptor antibodies, so none of those match. The correct answer is coeliac disease.
Step 2: Serum anti-endomysial antibodies (EMA) are highly suggestive of coeliac disease because they have both high sensitivity and high specificity. They are therefore a key serological screening test for this condition.
Step 3: Other supportive antibodies are tissue transglutaminase and antigliadin antibodies, and the treatment is a strict gluten free diet. Myasthenia gravis is screened with anti-acetylcholine receptor antibodies, autoimmune hepatitis with anti smooth muscle and ANA, and Graves disease with TSH receptor antibodies, so none of those match. The correct answer is coeliac disease.
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