Question:

Amino acid binding site of $tRNA$ is

Updated On: Aug 8, 2023
  • $5'$ end
  • $T\,\Psi\,C$ loop
  • $DHU$ loop
  • $3'$ end
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The Correct Option is D

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Answer (d) $3'$ end
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Ans: tRNA helps in the process of protein synthesis. It helps in the transport of amino acids to the specific site, so that correct amino acids are incorporated. It has a clover leaf like structure and has four arms. 

  • The acceptor arm is the one that is the amino acid binding site. It has a typical sequence present that is 5’-CCA-3’. The amino acid will come and bind covalently to the 3’ end. 
  • TΨ C arm that will help in maintaining the  stability of the tRNA. 
  • The D arm contains dihydrouridine, which is a modified nucleotide that helps in the folding and stability of tRNA. 
  • Anticodon arm is the one that will read the sequence codon on the mRNA. This site will contain the anticodon which will be complementary to the sequence on the mRNA. 
  • Variable arm is an extra arm. 
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Concepts Used:

The Molecular Basis of Inheritance

DNA Replication:

DNA synthesis is commenced at particular points within the DNA strand referred to as ‘origins’, which are certain coding regions. There are numerous origin sites, and when replication of DNA starts, these sites are mentioned as replication forks. Within the replication, the complex is the enzyme DNA Helicase, so that they can be utilized as a template for replication. DNA Primase is another enzyme that's essential in DNA replication.

RNA:

Ribonucleic acid (RNA) is an essential biological macromolecule that exists all together in biological cells. It is principally involved in the synthesis of proteins, that carry the messenger instructions from DNA, which itself contains the genetic instructions needed for the event and maintenance of life. In some viruses, RNA, in spite of DNA, carries genetic information.

Genetic Code:

Genetic code is the term we use in the manner that the four bases of DNA--the A, C, G, and Ts--are strung together in a way that the ribosome, the cellular machinery, can read them and switch them into a protein. In the ordering, every three nucleotides during a row count as a triplet and code for one amino alkanoic acid.

Read More: Molecular Basis of Inheritance