Question:

According to NCEP-ATP III criteria, which of the following is NOT included in the diagnosis of metabolic syndrome?

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The metabolic syndrome lipid criteria are about triglycerides and HDL, not this one.
Updated On: Jun 23, 2026
  • High LDL
  • Hypertriglyceridemia
  • Central obesity
  • Hypertension
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The Correct Option is A

Solution and Explanation

Step 1: NCEP-ATP III defines metabolic syndrome by 5 criteria, and a diagnosis needs any 3 of them:
- Central obesity (raised waist circumference)
- Elevated triglycerides (>150 mg/dL)
- Low HDL cholesterol (men <40, women <50 mg/dL)
- Raised blood pressure (>130/85 mm Hg)
- Raised fasting glucose (>100 mg/dL)
Step 2: The lipid criteria are high triglycerides and low HDL. LDL is NOT part of the definition.
Step 3: So hypertriglyceridemia, central obesity and hypertension are all included, while high LDL is the exception. The correct answer is high LDL.
Ref: DM Vasudevan, Textbook of Biochemistry, 6th edn, pg 286.
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