Question:

A subunit vaccine of CoxAbic contains

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CoxAbic Subunit Vaccine: Prepared from Gametocytes of Eimeria maxima (APGA Gam56/82). Immunizes breeder hens $\rightarrow$ Passive yolk immunity to chicks.
  • Precocious line Eimeria tenella
  • Gametocytes of Eimeria brunetti
  • Schizonts of Eimeria necatrix
  • Gametocytes of Eimeria maxima
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The Correct Option is D

Solution and Explanation


Step 1: Understanding the Concept:

Maternal coccidiosis vaccination in poultry using affinity-purified gametocyte surface antigens (APGA) to confer passive yolk immunoglobulin protection to chicks.

Step 2: Detailed Explanation:

CoxAbic (Poultry Coccidiosis Subunit Vaccine):
- The world's first commercial subunit vaccine developed against avian coccidiosis.
- It contains affinity-purified gametocyte antigens (APGA) extracted from the sexual sexual stage (Gametocytes) of {Eimeria maxima (specifically Gam56 and Gam82 glycoproteins).
- Administered to broiler breeder hens; the maternal IgG (IgY) antibodies produced against wall-forming gametocyte antigens are transferred via egg yolk to newly hatched progeny chicks, blocking oocyst wall formation and conferring broad passive cross-protection against E. tenella, E. maxima, and E. acervulina.

Step 3: Final Answer:

Thus, CoxAbic contains Gametocytes of Eimeria maxima, corresponding to option (D).
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