Question:
A patient complains of painful blisters around the angle of the mouth. Identify the condition.
A patient complains of painful blisters around the angle of the mouth. Identify the condition.
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Recurrent grouped vesicles right on the lip suggest a herpes simplex cold sore.
Updated On: Jun 23, 2026
- Herpes labialis
- Herpangina
- Herpes zoster
- Epstein-Barr
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The Correct Option is A
Solution and Explanation
Step 1: Painful grouped vesicles clustered at the lip and angle of the mouth are cold sores, that is herpes labialis, caused by herpes simplex virus (usually HSV-1).
Step 2: The typical course is a burning or tingling pain, then small blisters or sores on the lip. A first attack can add fever, sore throat and enlarged lymph nodes.
Step 3: Why not the others: herpangina (Coxsackie A) gives vesicles and ulcers on the soft palate and oropharynx, not the lip. Herpes zoster follows a dermatome and does not centre on the mouth angle. Epstein-Barr causes infectious mononucleosis with pharyngitis and lymphadenopathy, not perioral blisters. Relapses stay on the lip and decrease after age 35. Ref: NCBI/PMC2602638.
Step 2: The typical course is a burning or tingling pain, then small blisters or sores on the lip. A first attack can add fever, sore throat and enlarged lymph nodes.
Step 3: Why not the others: herpangina (Coxsackie A) gives vesicles and ulcers on the soft palate and oropharynx, not the lip. Herpes zoster follows a dermatome and does not centre on the mouth angle. Epstein-Barr causes infectious mononucleosis with pharyngitis and lymphadenopathy, not perioral blisters. Relapses stay on the lip and decrease after age 35. Ref: NCBI/PMC2602638.
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