Question:
A new class of anthelmintic monepantel is member of
A new class of anthelmintic monepantel is member of
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Modern Anthelmintic Classes:
Amino-Acetonitrile Derivatives (AAD) = Monepantel (Zolvix).
Spiroindoles = Derquantel.
Cyclic Depsipeptides = Emodepside.
Amino-Acetonitrile Derivatives (AAD) = Monepantel (Zolvix).
Spiroindoles = Derquantel.
Cyclic Depsipeptides = Emodepside.
Updated On: Sep 7, 2026
- Amidine group
- Salicylanilide group
- Amino-acetonitrile derivatives
- Macrocyclic lactone
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Verified By Collegedunia
The Correct Option is C
Solution and Explanation
Step 1: Understanding the Concept:
Monepantel represents a novel chemical class of anthelmintics targeting nematode-specific DEG-3 DES-2 nicotinic acetylcholine receptor subunits.
Step 2: Detailed Explanation:
Monepantel (Zolvix):
- Represents the fourth novel class of modern broad-spectrum anthelmintics discovered in 2008, chemically designated as Amino-Acetonitrile Derivatives (AADs).
- Acts as a positive allosteric modulator on nematode-specific DEG-3 ACR-23 nicotinic acetylcholine receptor (nAChR) subunits, causing spastic muscular paralysis in nematodes.
- Completely effective against multi-drug resistant gastrointestinal nematodes resistant to benzimidazoles, levamisole, and macrocyclic lactones.
Step 3: Final Answer:
Therefore, monepantel is a member of Amino-acetonitrile derivatives, matching option (C).
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