Question:

A 26-year-old female presents with oral ulcers, photosensitivity and a malar (butterfly) rash on the face that spares the nasolabial folds on both sides. What is the most likely diagnosis?

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Young woman, oral ulcers, photosensitivity, malar rash sparing nasolabial folds equals lupus.
Updated On: Jun 23, 2026
  • Sturge-Weber syndrome
  • SLE
  • Dermatitis
  • Psoriasis
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The Correct Option is B

Solution and Explanation

Step 1: The patient is a young woman, the typical demographic for systemic lupus erythematosus (SLE), an autoimmune connective tissue disease.
Step 2: The triad of oral ulcers, photosensitivity and a malar (butterfly) rash are all American College of Rheumatology classification criteria for SLE. The malar rash characteristically spares the nasolabial folds, exactly as described, which is a strong clue to lupus.
Step 3: Sturge-Weber (a) is a port-wine stain in a trigeminal distribution with seizures, not photosensitivity and ulcers. Dermatitis (c) and psoriasis (d) do not cause oral ulcers or photosensitivity with a nasolabial-sparing malar rash.
Step 4: The constellation fits SLE, so option b is correct.
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